Cellular functions of the ADF/cofilin family at a glance
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Cellular functions of the ADF/cofilin family at a glance.
The actin depolymerizing factor (ADF)/cofilin family comprises small actin-binding proteins with crucial roles in development, tissue homeostasis and disease. They are best known for their roles in regulating actin dynamics by promoting actin treadmilling and thereby driving membrane protrusion and cell motility. However, recent discoveries have increased our understanding of the functions of t...
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Rab GTPases control intracellular membrane traffic by recruiting specific effector proteins to restricted membranes in a GTPdependent manner. In this Cell Science at a Glance and the accompanying poster, we highlight the regulation of Rab GTPases by proteins that control their membrane association and activation state, and provide an overview of the cellular processes that are regulated by Rab ...
متن کاملCellular functions of Rab GTPases at a glance.
Rab GTPases control intracellular membrane traffic by recruiting specific effector proteins to restricted membranes in a GTP-dependent manner. In this Cell Science at a Glance and the accompanying poster, we highlight the regulation of Rab GTPases by proteins that control their membrane association and activation state, and provide an overview of the cellular processes that are regulated by Rab...
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a glance Pierre D. McCrea1,2,* and Dongmin Gu1,2 1Department of Biochemistry and Molecular Biology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA 2Program in Genes and Development, University of Texas Graduate School of Biomedical Sciences, Houston, TX 77030, USA *Author for correspondence ([email protected]) Journal of Cell Science 123, 637-642 © 2010. Published...
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Three families of cytoskeletal motor protein – the myosins, kinesins and dyneins – have evolved to mediate transport of cells and of structures and materials within cells in eukaryotes. Whereas myosin uses actin polymers to carry out its tasks, kinesin and dynein are microtubule-associated motors. Dyneins use energy from ATP hydrolysis to power a wide variety of cellular functions. Although at ...
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ژورنال
عنوان ژورنال: Journal of Cell Science
سال: 2016
ISSN: 1477-9137,0021-9533
DOI: 10.1242/jcs.187849